Andreas Peschel studied Biology in Bochum and Tübingen, Germany, and obtained Diploma and PhD degrees in Microbiology. He held postdoctoral positions in the labs of Friedrich Götz in Tübingen and of Jos van Strijp in Utrecht (The Netherlands) focusing on Staphylococcus aureus cell wall and host/pathogen interaction. After a period as Assistant Professor at the Faculty of Biology he accepted a call to the Medical Microbiology and Hygiene Department as a Professor of Cellular and Molecular Microbiology in Tübingen. His lab studies staphylococcal biology with special interests in teichoic acids, evasion of antimicrobial defense mechanisms, and proinflammatory bacterial molecules.
Staphylococcus aureus is a constituent of the nasal microbiota in 20-30% of the human population and also represents the most frequent cause of life-threatening invasive infections in the northern hemisphere. The individual predisposition to S. aureus colonization and the transition from commensal to pathogenic life-styles represent exciting examples of microbe-host coevolution and adaptation processes. We are studying the underlying principles of S. aureus nasal colonization, metabolic adaptation and fitness, and resistance to defensin-like antimicrobial peptides.