PortfolioStephanie Grond

Personendaten

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Akademischer Titel:
Prof. Dr.
Name:
Stephanie Grond
Einrichtungen:
Mathematisch-Naturwissenschaftliche Fakultät
Universität Tübingen
Institut für Organische Chemie
Fachbereich Chemie

Kontaktdaten

Forschungsschwerpunkte

Getting on the Track of Nature: Chemical Diversity and Regulation Activity

A primary goal of our natural products research is to get further insights into the secondary metabolism of microorganisms and to generate a novel diversity of secondary metabolites. The research is based on previous work with biological derivatisation methods to enhance the diversity of secondary metabolites from microorganisms. We are interested in a new approach to novel metabolites by extension to genetic studies in interdisciplinary projects. Regulation acitivties concerning differentiation mechanisms and the investigation of the biosynthesis of metabolites is of our interest. For our aims Aspergillus sp., Streptomyces sp. and some other microorganisms with marked differentiation activities are selected. 

The main focus are isolation, structure elucidation and chemical characterization of the new secondary metabolites. Concise strategies to elucidate structures incorporate established methods of HPLC, modern spectroscopy (e.g. 2-D-NMR, MS/MS) and data bases.  Our institute of  bioorganic chemistry houses own microbiological technology besides chemical laboratories and an S1-security lab. Microbiological work revolves around stock cultures, cultivations in flasks and in various stirring vessels or an air-loop fermentor. Different whole cell assays are carried out. Additionally we work on a broad exploitation of the biological activity of the natural compounds with therapeutic targets in interdisciplinary cooperations with external research groups.

Patente

22.04.2021
Stephanie Grond, Nadine Schilling
29.07.2021
24.09.2024 (erloschen)
Stephanie Grond, Julian Schmid
Jaime Felipe Guerrero Garzón, Tilmann Weber, Axel Zeeck
24.11.2017
Klaus Brilisauer, Karl Forchhammer, Stephanie Grond
23.03.2015
02.05.2018
Stephanie Grond, Daniela Janek, Hubert Kalbacher, Martin Konnerth, Bernhard Krismer, Andreas Peschel, Nadine Schilling, Alexander Zipperer
23.03.2015
Stephanie Grond, Daniela Janek, Hubert Kalbacher, Martin Konnerth, Bernhard Krismer, Andreas Peschel, Nadine Schilling, Alexander Zipperer

Projekte

2019 - 2023
Heike Brötz-Oesterhelt
Deutsche Forschungsgemeinschaft e.V. (DFG)
2012 - 2021
Karl Forchhammer
Deutsche Forschungsgemeinschaft e.V. (DFG)

Kooperationen

Akademie věd České republiky (AV ČR)
Prag, Tschechien
University of Kentucky
Lexington, Kentucky, Vereinigte Staaten
Danmarks Tekniske Universitet (DTU)
Kongens Lyngby, Dänemark
Guangdong Ocean University (GDOU)
Zhanjiang, Guangdong, China

Publikationen

Hilfe

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