FIT - Portfolio

Person data

Academic title:

Prof. Dr.

Name:

Klaus Schulze-Osthoff

Organizational units:

Faculty of Medicine

University of Tübingen

Cluster of Excellence: Image-Guided and Functionally Instructed Tumor Therapies (iFIT)

Centers or interfaculty scientific institutions

Contact data

Curriculum vitae

Education (from bachelor’s degree)

Year	Degree	College of University	Field of study
1985	Diploma Biology	University of Münster	Biochemistry
1986	PhD, Dr. rer. nat.	University of Münster	Tumor biology
1994	Postdoctoral thesis	University of Heidelberg	Tumor Immunology
	(Habilitation)

Research Experience

Period	Institution	Position	Discipline
2009 –	University of Tübingen,	Professor (W3)	Tumor Biology,
	Institute for Biochemistry		Biochemistry

2001 – 2008	University of Düsseldorf,	Professor (C4)	Tumor Biology,
	Institute of Mol. Medicine		Molecular Medicine

1999 – 2001	University of Münster,	Professor (C3)	Tumor Immunology,
	Dept. of Immunology		Tumor Biology
	and Cell Biology

1997 – 1998	University of Tübingen,	Professor (C3)	Tumor Biology,
	Dept. Internal Medicine		Molecular Hepatology

1995 – 1997	University of Freiburg,	Assist. Professor (C2)	Tumor Biology,
	Institute of Biochemistry &		Signal Transduction
	Molecular Biology

1992 – 1995	German Cancer	Senior scientist	Tumor Immunology,
	Research Center,		Tumor Biology
	Heidelberg

1990 – 1992	Laboratory of Mol. Biology,	Postdoctoral researcher	Tumor Biology,
	University of Ghent, Belgium		Molecular Biology

1988 – 1990	Institute of	Postdoctoral researcher	Tumor Biology
	Exp. Dermatology,
	University of Münster

Honours

1990 – 1995	Fellowship Award for Infectiology, German Ministry for Education and Research (BMBF)
1995	Award "Skin and Environment", Grünenthal AG, Germany
2008	Innovation Award for German University Medicine, Berlin
2011 –	Board Member, Biocheck GmbH, Münster, Germany
2009 – 2013	Scientific director of the Comprehensive Cancer Center (CCC) Tübingen
2008 –	Board Member, Comprehensive Cancer Center Tübingen–Stuttgart
2009 – 2012	Member of the scientific committee "Emerging and Newly Identified Health Risks" (SCENIHR) of the European Commission
2011 – 2013	Spokesperson of the Collaborative Research Centre (SFB) 773
2011 –	Local Coordinator of the German Consortium for Translational Cancer Research (DKTK)
2012 –	Scientific Advisory Board Member, Comprehensive Cancer Center Düsseldorf
2013 –	Fellow of the German Cancer Research Center (DKFZ, Heidelberg)

Research focus

Tumor Biology, Inflammation Research, Cytokines, Transcription Factors, NF-κB, Apoptosis Senescence, Stress Signaling

Biographical Sketch

Klaus Schulze-Osthoff heads the Department of Molecular at the Interfaculty Institute of Biochemistry. For several years he studied cell death processes involved in tumor therapy and immune responses. He was the first to show that mitochondrial alterations are important for cell death processes. His group also discovered that caspases are crucial mediators of death receptor signaling. More recent research focuses on novel coactivators of transcription factor NF-κB and their role in immune cell differentiation and tumor therapy resistance. From 2009 to 2013 Klaus Schulze-Osthoff was the Scientific Director of the Comprehensive Cancer Centre (CCC) Tübingen, and from 2011 to 2013 he has been the spokesperson of the Collaborative Research Centre (SFB 773) on therapy resistance of solid tumors. Since 2011 he is the Tübingen’s coordinator of in the German Consortium for Translational Cancer Research (DKTK).