ProjectImpact of acute hemodynamic effects on myocardial remodelling and mid-term durability after transcatheter…

Basic data

Title:
Impact of acute hemodynamic effects on myocardial remodelling and mid-term durability after transcatheter edge-to-edge repair of mitral regurgitation using PASCAL®
Duration:
16/07/2019 to 31/12/2022
Abstract / short description:
Reduction of MR using one/several PASCAL device(s) leads to hemodynamic changes (decreased atrial and ventricular loading volumes and pressures as well as systolic pulmonary artery pressure) which result in reversed cardiac remodelling: reduced left ventricular dilatation, improved left and right ventricular function with concomitant improvement of pulmonary hypertension and a reduction of mitral regurgitation over time (i.e. 6 to 12 months).
This project aims to investigate the periprocedural haemodynamic changes and their impact on myocardial remodelling and the durability of the device 6 months after a mitral valve TEER using a PASCAL system.

Involved staff

Managers

Department of Internal Medicine
Hospitals and clinical institutes, Faculty of Medicine
Faculty of Medicine
University of Tübingen
Faculty of Medicine
University of Tübingen

Contact persons

Faculty of Medicine
University of Tübingen
Faculty of Medicine
University of Tübingen
Faculty of Medicine
University of Tübingen

Other staff

Faculty of Medicine
University of Tübingen

Local organizational units

Internal Medicine Department III
Department of Internal Medicine
Hospitals and clinical institutes, Faculty of Medicine

Funders

Nyon, Switzerland
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