ProjectICD - OVIT - GBM – Nachweis des immunogenen Zelltods bei onkolytischer Virotherapie des Glioblastoms
Basic data
Acronym:
ICD - OVIT - GBM
Title:
Nachweis des immunogenen Zelltods bei onkolytischer Virotherapie des Glioblastoms
Duration:
21/03/2022 to 31/12/2022
Abstract / short description:
Oncolytic viruses (OVs) are promising candidates to treat highly malignant, solid tumors like glioblastoma (GBM). Additionally to the OV-mediated killing of tumor cells, OVs stimulate both unspecific, but also specific anti-tumoral immune cell activation. In this study we will determine the induction of immunogenic cell death by our OVs alone and in combination with the blockade of immune checkpoint proteins.
Keywords:
immunogener Zelltod
onkolytische Viren
Glioblastom
Involved staff
Managers
University Department of Neurology
Hospitals and clinical institutes, Faculty of Medicine
Hospitals and clinical institutes, Faculty of Medicine
Local organizational units
Hertie Institute for Clinical Brain Research (HIH)
Non-clinical institutes
Faculty of Medicine
Faculty of Medicine
Funders
Tübingen, Baden-Württemberg, Germany