ProjectDie Rolle des menschlichen parietalen und visuellen Kortex im visuellen Arbeitsgedächtnis, untersucht durch…

Basic data

Title:
Die Rolle des menschlichen parietalen und visuellen Kortex im visuellen Arbeitsgedächtnis, untersucht durch simultanes fMRT-TMS
Duration:
4/1/2022 to 3/31/2025
Abstract / short description:
The human parietal cortex and early visual cortex have been hypothesized to play an important role in visual working memory as human functional magnetic resonance imagining (fMRI) decoding studies revealed fine- grained working memory information in both regions. The content of working memory information in the early visual areas is thought to be mediated via feedback connections from higher-level areas, such as the parietal cortex. However, causal evidence supporting these observations is still missing. In the current proposal we present two experiments designed to investigate the causal involvement of the human parietal and visual cortex in visual working memory. For this, we will combine transcranial magnetic stimulation (TMS) with concurrent fMRI and psychophysics to answer the following questions: (1) does parietal cortex play a causal role in maintaining visual working memory? (2) does parietal cortex convey working memory content to early visual cortex? (3) is early visual cortex causally involved in the maintenance of visual working memory, and is this task-dependent? The combination of fMRI and TMS using a state-of-the-art setup will allow us to measure behavioural effects as well as neural effects across the whole-brain, and test central predictions of leading theories of working memory and previous correlational observations.
Keywords:
fMRI
functional magnetic resonance imaging, funktionelle Magnetresonanztomographie
perception
Wahrnehmung
TMS (transcranial magnetic stimulation)
visual perception
working memory
Gedächtnis

Involved staff

Managers

University Department of Neurology
Hospitals and clinical institutes, Faculty of Medicine
Institute of Psychology
Department of Psychology, Faculty of Science

Local organizational units

Department of Psychology
Faculty of Science
University of Tübingen
Werner Reichardt Center for Integrative Neuroscience (CIN)
Centers
University of Tübingen

Funders

Bonn, Nordrhein-Westfalen, Germany
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