PhAcSAM

Phosphatidsäure reguliert die Morphogenese am sprossapikalen Meristem

01/01/2022 to 31/12/2024

In plants, the emergence of all aerial organs occurs during post-embryogenesis from an organized stem cell niche called the shoot apical meristem (SAM) The role of many biochemical regulators such as transcription factors, microRNA, hormones, and peptides as well as structural elements such as the cell wall have been extensively studied in meristem function.
Lipids are major components of the plasma membrane and are not only structural components but play a crucial role in signalling. Low abundant lipids are labelled as ‘signalling’ since they have fast turn-over. Phosphatidic acid (PA) is a signalling lipid able to tune auxin protein carrier localisation but also microtubule dynamics, that are key factors required for primordium initiation at the SAM. Nevertheless, the role of PA in regulating morphogenesis at the SAM remains unknown.
Understanding how the lipid composition of the plasma membrane tunes protein localization and function will provide new insight into SAM regulation, especially by studying these processes at both the tissue and cell level.