ProjectAltoida – Plasma NfL, NT1 tau and pTau181 the prediction of POCD in elderly people who undergo cardiac surgery

Basic data

Acronym:
Altoida
Title:
Plasma NfL, NT1 tau and pTau181 the prediction of POCD in elderly people who undergo cardiac surgery
Duration:
5/1/2021 to 6/1/2021
Abstract / short description:
This biomarker project aims to aid stratification of individual risk profiles for development of postoperative cognitive dysfunction (POCD) in elderly people who undergo cardiac surgery using the most promising ultra-sensitive blood-based assays for both AD-specific tau fragments (NT1 tau and tau phosphorylated at threonine-181) and an axonal destruction marker (Neurofilament Light Chain, NfL).
Keywords:
biomarker
Biomarker
Neurofilament Light Chain
Geriatrie
postoperative kognitive Dysfunktion
Kognition

Involved staff

Managers

Faculty of Medicine
University of Tübingen
University Department of Neurology
Hospitals and clinical institutes, Faculty of Medicine

Contact persons

University Department of Neurology
Hospitals and clinical institutes, Faculty of Medicine

Local organizational units

Department of Neurology with Focus on Neurodegenerative Disorders
University Department of Neurology
Hospitals and clinical institutes, Faculty of Medicine
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