ProjectDirect sensing of K+ efflux by the NLRP3 Inflammasome in response to Staphylococcal toxins
Direct sensing of K+ efflux by the NLRP3 Inflammasome in response to Staphylococcal toxins
01/04/2021 to 31/03/2022
Abstract / short description:
K+ efflux is a common danger signal for activating NLRP3 inflammasome. During infection, Staphylococcal toxins are responsible to produce the efflux of K+ in macrophages, leading the scape of bacteria..
Local organizational units
Interfaculty Institute for Cell Biology (IFIZ)