ProjectDirect sensing of K+ efflux by the NLRP3 Inflammasome in response to Staphylococcal toxins

Basic data

Title:
Direct sensing of K+ efflux by the NLRP3 Inflammasome in response to Staphylococcal toxins
Duration:
01/04/2021 to 31/03/2022
Abstract / short description:
K+ efflux is a common danger signal for activating NLRP3 inflammasome. During infection, Staphylococcal toxins are responsible to produce the efflux of K+ in macrophages, leading the scape of bacteria..

Involved staff

Managers

Faculty of Medicine
University of Tübingen

Local organizational units

Immunology
Interfaculty Institute for Cell Biology (IFIZ)
Interfaculty Institutes

Funders

Bonn, Nordrhein-Westfalen, Germany
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