ProjectAdCAR tuning – AdCAR-T tuning in solid cancer

Basic data

Acronym:
AdCAR tuning
Title:
AdCAR-T tuning in solid cancer
Duration:
8/19/2019 to 8/16/2021
Abstract / short description:
Adapter CAR T cells (AdCAR-T) are genetically modified to enhance in vivo proliferation and persistence as well as to overcome the immunosuppressive tumor microenvironment in terms of penetration into the tumor and to circumvent the negative feedback by immunosuppressive ligands and cytokines expressed and released by the tumor, respectively.

Involved staff

Managers

Schlegel, Patrick
Faculty of Medicine
University of Tübingen

Contact persons

Faculty of Medicine
University of Tübingen

Local organizational units

Paediatrics Department I and Polyclinic
University Children’s Hospital - Department of Paediatrics
Hospitals and clinical institutes, Faculty of Medicine

Funders

Ravensburg, Baden-Württemberg, Germany
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