ProjectVG-EXCEL – Vietnamesisch - Deutsches Exzellenz-Studienzentrum

Basic data

Acronym:
VG-EXCEL
Title:
Vietnamesisch - Deutsches Exzellenz-Studienzentrum
Duration:
8/1/2017 to 7/31/2022
Abstract / short description:
The Vietnamese-German Center of Excellence (VG-EXCEL) was founded as part of the Vietnamese-German Center for Medical Research (VG-CARE) on the basis of the longstanding collaboration between the Institute of Tropical Medicine at Eberhard-Karls-University in Tübingen and the 108 Military Central Hospital in Hanoi. By declaration of the Vietnamese Ministry of Defense, VG-CARE received the official status of an independent, non-profit legal entity and was inaugurated on January 16, 2018 in the presence of the Vietnamese Deputy Minister of Defense.
The main goal of the VG-EXCEL project is to create a platform for the implementation of ICH-GCP/GCLP-compliant clinical studies on new treatment strategies, vaccinations, diagnostic systems as well as interventional and observational studies on various infectious diseases in the region.
Further goals of the project include support and expansion of VG-CARE's research capacities and the conduct of a clinical phase II study according to ICH-GCP/GCLP standards (Phase II Randomised, Double Blind, Placebo Controlled Trial of Neoadjuvant Artesunate in Stage II/III Colorectal Cancer in Vietnamese Patients [NeoART-v study]). Artesunate is an inexpensive, orally applicable and widely used medication for malaria, which has antitumor properties. A total of 200 patients are to be recruited by the end of 2021.
This study provides an excellent opportunity for Vietnamese scientists to be trained in the conduct of clinical trials according to international GCP/GCLP standards. At the same time, young scientists and students from Germany and Vietnam are supported in obtaining their academic degrees (MSc, MD, PhD).
In addition, VG-EXCEL will be expanded as a central platform for clinical studies of various German and Vietnamese, but also international institutions. For example, a joint study 'Human coevolution with Bifidobacterium and the microbial contribution to lactose tolerance in Vietnam' was successfully carried out with the Max Planck Institute for Developmental Biology, Tübingen.
In addition, the centre is now represented in numerous international consortia and congresses. VG-EXCEL is currently the only institution in Vietnam that is able to conduct ICH (International Council for Harmonization) -compliant clinical studies according to GCP/GCLP standards. A data monitoring committee is set up for each study and REDCAP, OpenClinica and other internet-based tools are used to manage, record, store and process all collected data.
Activities to promote the profile of scientists and the continuous expansion of long-term education and research concepts that are to become part of routine clinical, laboratory and research practices in Vietnam are an integral part of VG-EXCEL. Overall, VG-EXCEL is intended to provide existing technologies, assays and diagnostic tools as an interactive platform and to support VG-CARE in upgrading diagnostic laboratories to reference laboratories.
Based on the unrestricted availability of well-characterised and documented biological samples of diseases that do not occur in Europe (infectious and tropical diseases), VG-EXCEL endeavours to establish appropriate biobanks that also benefit German partners.

Involved staff

Managers

Faculty of Medicine
University of Tübingen

Local organizational units

Department VII, Tropical Medicine
Department of Internal Medicine
Hospitals and clinical institutes, Faculty of Medicine

Funders

Bonn, Nordrhein-Westfalen, Germany
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