Project3D Skin Models

Basic data

3D Skin Models
01/07/2019 to 30/06/2023
Abstract / short description:
Mouse and human skin differ significantly in cellular architecture and physiology which makes it difficult to extrapolate from mouse studies to humans. In vitro 3-dimensional (3D) human skin equivalents (HSE) including defined immune cell subsets or genetically manipulated cells can bridge the gap between traditional 2D cell culture and animal models and more likely reflect the complexity involved in human skin homeostasis. Using our long-standing expertise in human 3D skin models we provide a service for the application of human 3D skin models to the TR156 groups depending on their specific needs.

Involved staff


Department of Dermatology
Hospitals and clinical institutes, Faculty of Medicine
Cluster of Excellence: Image-Guided and Functionally Instructed Tumor Therapies (iFIT)
Centers or interfaculty scientific institutions
Research training group: Non-canonical G protein signaling pathways
Research training groups

Local organizational units

Department of Dermatology
Hospitals and clinical institutes
Faculty of Medicine


Bonn, Nordrhein-Westfalen, Germany

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