ProjektClosed-loop TMS triggered by real-time cortical excitability states for neural rehabilitation of patients with…
Grunddaten
Titel:
Closed-loop TMS triggered by real-time cortical excitability states for neural rehabilitation of patients with disorders of consciousness
Laufzeit:
01.10.2019 bis 31.03.2021
Abstract / Kurz- beschreibung:
This project aims at establishing a more efficient rTMS protocol for neural rehabilitation of DOC patients, by testing an EEG-TMS closed-loop system in DOC patients. The main aims are:
(1) To evaluate the effects of rTMS triggered by different phases of the ongoing alpha rhythm in the left dorsolateral prefrontal cortex (DLPFC) on the DOC patients;
(2) To investigate the interaction between the instantaneous excitability state with the cortical responses to rTMS by characteristics derived from resting-state EEG and TMS-EEG;
(3) To improve the traditional open-loop rTMS strategy and develop methods for applying an EEG-TMS protocol on neural rehabilitation of DOC patients.
(1) To evaluate the effects of rTMS triggered by different phases of the ongoing alpha rhythm in the left dorsolateral prefrontal cortex (DLPFC) on the DOC patients;
(2) To investigate the interaction between the instantaneous excitability state with the cortical responses to rTMS by characteristics derived from resting-state EEG and TMS-EEG;
(3) To improve the traditional open-loop rTMS strategy and develop methods for applying an EEG-TMS protocol on neural rehabilitation of DOC patients.
Beteiligte Mitarbeiter/innen
Leiter/innen
Neurologische Universitätsklinik
Kliniken und klinische Institute, Medizinische Fakultät
Kliniken und klinische Institute, Medizinische Fakultät
Lokale Einrichtungen
Abteilung Neurologie mit Schwerpunkt neurovaskuläre Erkrankungen
Neurologische Universitätsklinik
Kliniken und klinische Institute, Medizinische Fakultät
Kliniken und klinische Institute, Medizinische Fakultät
Geldgeber
Bonn, Nordrhein-Westfalen, Deutschland