ProjectFOR2314, TP10 – MYC-Dstabilisation by conformation-changing AurKa ligands

Basic data

Acronym:
FOR2314, TP10
Title:
MYC-Dstabilisation by conformation-changing AurKa ligands
Duration:
01/09/2018 to 31/08/2021
Abstract / short description:
The overall objectives of this project are to understand how conformation-changing Aurora-A ligands exert their therapeutic effect in MYC-driven tumors and to mechanistically explore and therapeutically develop Aurora-A mediated MYC-targeting as a therapeutic strategy for the treatment of therapy-resistant solid tumors

Involved staff

Managers

Faculty of Science
University of Tübingen
Pharmaceutical Institute
Department of Pharmacy and Biochemistry, Faculty of Science
Baden-Württemberg Center for Brazil and Latin America
Branch offices and other central facilities
Cluster of Excellence: Image-Guided and Functionally Instructed Tumor Therapies (iFIT)
Centers or interfaculty scientific institutions

Contact persons

Faculty of Medicine
University of Tübingen
Cluster of Excellence: Image-Guided and Functionally Instructed Tumor Therapies (iFIT)
Centers or interfaculty scientific institutions

Local organizational units

Pharmaceutical Institute
Department of Pharmacy and Biochemistry
Faculty of Science

Funders

Bonn, Nordrhein-Westfalen, Germany
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