ProjectFOR2314, TP10 – MYC-Dstabilisation by conformation-changing AurKa ligands
Basic data
Acronym:
FOR2314, TP10
Title:
MYC-Dstabilisation by conformation-changing AurKa ligands
Duration:
01/09/2018 to 31/08/2021
Abstract / short description:
The overall objectives of this project are to understand how conformation-changing Aurora-A ligands exert their therapeutic effect in MYC-driven tumors and to mechanistically explore and therapeutically develop Aurora-A mediated MYC-targeting as a therapeutic strategy for the treatment of therapy-resistant solid tumors
Involved staff
Managers
Faculty of Science
University of Tübingen
University of Tübingen
Pharmaceutical Institute
Department of Pharmacy and Biochemistry, Faculty of Science
Department of Pharmacy and Biochemistry, Faculty of Science
Baden-Württemberg Center for Brazil and Latin America
Branch offices and other central facilities
Branch offices and other central facilities
Cluster of Excellence: Image-Guided and Functionally Instructed Tumor Therapies (iFIT)
Centers or interfaculty scientific institutions
Centers or interfaculty scientific institutions
Contact persons
Faculty of Medicine
University of Tübingen
University of Tübingen
Cluster of Excellence: Image-Guided and Functionally Instructed Tumor Therapies (iFIT)
Centers or interfaculty scientific institutions
Centers or interfaculty scientific institutions
Local organizational units
Pharmaceutical Institute
Department of Pharmacy and Biochemistry
Faculty of Science
Faculty of Science
Funders
Bonn, Nordrhein-Westfalen, Germany