ProjectTranscan 3 Verbund: HLA-Ligandomanalyse von ATRT-Tumorgewebeproben
Basic data
Title:
Transcan 3 Verbund: HLA-Ligandomanalyse von ATRT-Tumorgewebeproben
Duration:
4/1/2015 to 3/31/2018
Abstract / short description:
Atypical teratoid/rhabdoid tumors (ATRT) are rare but highly malignant neuroectodermal tumors. Here, we will analyze the ATRT peptidome by directly eluting peptides from tumor HLA molecules and sequence analysis via mass spectrometry. Subsequently, the most relevant peptides will be tested for immunogenicity in naïve CD8+ T cells from healthy donors and selected patients
Involved staff
Managers
Immunology
Interfaculty Institute for Cell Biology (IFIZ), Interfaculty Institutes
Interfaculty Institute for Cell Biology (IFIZ), Interfaculty Institutes
Local organizational units
Immunology
Interfaculty Institute for Cell Biology (IFIZ)
Interfaculty Institutes
Interfaculty Institutes
Funders
Bonn, Nordrhein-Westfalen, Germany