ProjectHFA-Spaag – Hector Fellow Projekt Salome Spaag

Basic data

Acronym:
HFA-Spaag
Title:
Hector Fellow Projekt Salome Spaag
Duration:
01/08/2024 to 31/07/2028
Abstract / short description:
Mutations in USH2A are one of the most common cause of Usher syndrome and Retinitis pigmentosa for which no cure exists so far. The project seeks to develop and validate a novel CRISPR technology based therapeutic approach targeting common mutations in the USH2A gene and to explore strategies for an inducible (switch-on/switch-off) transgene expression system implemented into an adenoviral-associated viral (AAV) vector for delivery into preclinical model systems.

Involved staff

Managers

Faculty of Medicine
University of Tübingen
Center for Ophthalmology
Hospitals and clinical institutes, Faculty of Medicine

Contact persons

Center for Ophthalmology
Hospitals and clinical institutes, Faculty of Medicine

Local organizational units

Research Center for Ophthalmology
Center for Ophthalmology
Hospitals and clinical institutes, Faculty of Medicine

Funders

Karlsruhe, Baden-Württemberg, Germany
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