ProjectYoFaPoCo – Yoga versus health education for persistent fatigue in patients with post-COVID-syndrome- Multicenter…

Basic data

Acronym:
YoFaPoCo
Title:
Yoga versus health education for persistent fatigue in patients with post-COVID-syndrome- Multicenter Randomised Controlled Trial
Duration:
01/06/2023 to 31/05/2026
Abstract / short description:
During the COVID-19 pandemic, five to ten percent of patients described persisting symptoms for over 3 months after an acute SARS-CoV-2 infection, defined by the WHO as post-COVID-syndrome. Symptoms most commonly described by patients are fatigue (58%), headache (44%), attention disorder (27%), dyspnea (24%), and insomnia (21%). While current research suggests a variety of causes for symptom persistence, the most debated mechanisms include immunologic dysfunction, autoinflammation, virus persistence, autonomic dysregulation, hypercapnia, hypoperfusion and microthrombi. For symptoms such as headache or insomnia, painkillers or sleep medication (e.g. melatonin) can bring relief. Whereas for symptoms such as fatigue or attention disorder, which have the most impact on patient-reported quality of life as well as participation in daily, social, and working life, treatment is more complex and should contain a bio-psycho-social multimodal approach. Physical activity should be part of a multimodal treatment as described in the AWMF S1-Long/Post-COVID-guideline, but in low to moderate intensity, to reduce the risk of triggering post exertional malaise or exacerbate fatigue symptoms. Yoga is one of the most effective treatments in cancer-related fatigue and can be modified to low and moderate intensity depending on patients’ fitness and fatigue level. Therefore, yoga, including asana (movement exercises), pranayama (breathing exercises) and dhyana (meditation), could potentially improve fatigue levels as well as insomnia, hypercapnia, hypoperfusion and dyspnea. To examine if yoga could be a feasible persistent fatigue treatment in patients with post-COVID-syndrome, this study examines the effect of yoga and routine care in comparison to health education and routine care on persistent fatigue in patients with post-COVID-syndrome.

Involved staff

Managers

Institute for General Practice and Interprofessional Care
Hospitals and clinical institutes, Faculty of Medicine

Contact persons

Faculty of Medicine
University of Tübingen

Local organizational units

Institute for General Practice and Interprofessional Care
Hospitals and clinical institutes
Faculty of Medicine

Funders

Essen, Nordrhein-Westfalen, Germany
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