ProjectDirect sensing of K+ efflux by the NLRP3 Inflammasome in response to Staphylococcal toxins

Basic data

Title:
Direct sensing of K+ efflux by the NLRP3 Inflammasome in response to Staphylococcal toxins
Duration:
01/04/2021 to 31/03/2022
Abstract / short description:
K+ effflux is a common danger sensor for activting NLRP3 inflammasome. Staphylococcal toxins during infections are responsible to produce the efflux of K+ in macrophages, promoting the scape of bacteria

Involved staff

Managers

Tapia Abellan, Ana
Faculty of Medicine
University of Tübingen

Local organizational units

Immunology
Interfaculty Institute for Cell Biology (IFIZ)
Interfaculty Institutes

Funders

Bonn, Nordrhein-Westfalen, Germany
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