ProjectDirect sensing of K+ efflux by the NLRP3 Inflammasome in response to Staphylococcal toxins

Basic data

Title:

Direct sensing of K+ efflux by the NLRP3 Inflammasome in response to Staphylococcal toxins

Duration:

01/04/2021 to 31/03/2022

Abstract / short description:

K+ effflux is a common danger sensor for activting NLRP3 inflammasome. Staphylococcal toxins during infections are responsible to produce the efflux of K+ in macrophages, promoting the scape of bacteria

Involved staff

Managers

Tapia Abellan, Ana

Faculty of Medicine
University of Tübingen

Local organizational units

Immunology

Interfaculty Institute for Cell Biology (IFIZ)
Interfaculty Institutes

Funders

Deutsche Forschungsgemeinschaft e.V. (DFG)

Bonn, Nordrhein-Westfalen, Germany