ProjectCSF neuroinflammatory signature in Alzheimer's disease and related proteopathies

Basic data

Title:
CSF neuroinflammatory signature in Alzheimer's disease and related proteopathies
Duration:
01/11/2022 to 31/10/2024
Abstract / short description:
The reaction of glial cells plays a central role in the pathogenesis of neurodegenerative disorders such as Alzheimer's and Parkinson's disease. However, measurable parameters to monitor this process in patients are still largely lacking. With the funding from the Cure Alzheimer's Fund, we now plan to identify a set of CSF markers that reflect neuroinflammatory stages in the brain. We then aim to develop a multipley assay that could be used to assess glial activation in liquid biopsies.
Keywords:
Alzheimer's disease
Alzheimer-Erkrankung
biomarker
Biomarker
CSF

Involved staff

Managers

University Department of Neurology
Hospitals and clinical institutes, Faculty of Medicine
University Department of Neurology
Hospitals and clinical institutes, Faculty of Medicine
Hertie Institute for Clinical Brain Research (HIH)
Non-clinical institutes, Faculty of Medicine

Local organizational units

Hertie Institute for Clinical Brain Research (HIH)
Non-clinical institutes
Faculty of Medicine

Funders

Wellesley Hills, Massachusetts, United States
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