Deutsches Förderprogramm für Retinologie - Molecular Profile of a triple cell culture AMD-model for the CFH Y402H risk variant

01.01.2025

The overall goal of the project is to build a Molecular Profile of a triple cell culture AMD-model for the CFH Y402H risk variant. Exploiting stem cell research and the use of differentiated retinal cells from stem cells, we will combine retinal pigment epithelium (RPE), retinal organoids, containing rod and cone photoreceptors, and microglia cells. Using this model we aim to better understand and treat retinal degeneration, especially the common form of it in the elderly population, which is age related macular degeneration