ProjectA2BipoLife – Adjuvante Psychotherapie zur Rückfallprävention während der frühen Lebensphase einer Bipolaren Störung
Basic data
Acronym:
A2BipoLife
Title:
Adjuvante Psychotherapie zur Rückfallprävention während der frühen Lebensphase einer Bipolaren Störung
Duration:
01/03/2015 to 30/09/2020
Abstract / short description:
To test three groups of hypotheses, regarding whether the addition of a specific, innovativ psychotherapy (SEKT) to psychiatric care in young bipolar patients in early stage of their disease
Primary: (1) reduces rate of relapse (development of new affective episode);
Secondary: (2) reduces missed days at work/school, days spent in hospitals, and health costs, improves medical treatment compliance and social functioning; (3) normalizes neurobiological functioning; (a) normalizes alterations in neural networks associated with emotion regulation and social cognition, i.e., reverses enhanced activation in the amygdala, attenuated activation in the medial prefrontal cortex; b) pre-treatment neural alterations in these systems will predict post-treatment outcome of SEKT, with the greatest improvement in SEKT for patients with the most pronounced neural alterations prior to treatment.
Primary: (1) reduces rate of relapse (development of new affective episode);
Secondary: (2) reduces missed days at work/school, days spent in hospitals, and health costs, improves medical treatment compliance and social functioning; (3) normalizes neurobiological functioning; (a) normalizes alterations in neural networks associated with emotion regulation and social cognition, i.e., reverses enhanced activation in the amygdala, attenuated activation in the medial prefrontal cortex; b) pre-treatment neural alterations in these systems will predict post-treatment outcome of SEKT, with the greatest improvement in SEKT for patients with the most pronounced neural alterations prior to treatment.
Keywords:
Bipolare Störung
Rückfallprävention
Psychotherapie
Involved staff
Managers
Faculty of Science
University of Tübingen
University of Tübingen
Institute of Psychology
Department of Psychology, Faculty of Science
Department of Psychology, Faculty of Science
Contact persons
Department of Psychiatry and Psychotherapy
Hospitals and clinical institutes, Faculty of Medicine
Hospitals and clinical institutes, Faculty of Medicine
Faculty of Medicine
University of Tübingen
University of Tübingen
Department of Psychiatry and Psychotherapy
Hospitals and clinical institutes, Faculty of Medicine
Hospitals and clinical institutes, Faculty of Medicine
Local organizational units
Department of Psychology
Faculty of Science
University of Tübingen
University of Tübingen
Funders
Bonn, Nordrhein-Westfalen, Germany