Project SOPHIA – Stratification of Obese Phenotypes to Optimize Future Obesity Therapy

Basic data

Acronym:
SOPHIA
Title:
Stratification of Obese Phenotypes to Optimize Future Obesity Therapy
Duration:
01/06/2020 to 31/05/2025
Abstract / short description:
The objective of SOPHIA is to increase the understanding of and optimise future treatment of obesity. We understand why this has been challenging: too often, clinicians, payers and patients do not consider obesity a disease. We propose that obesity is in fact a set of complex and chronic diseases that should be taken just as seriously as other heterogeneous chronic conditions. Here, we define diseases of obesity in the context of (a) the risks of complications linked to obesity and (b) the responses the diseases have to various treatments (diets, exercise, drugs and surgery). SOPHIA will identify and characterise clinically-meaningful subpopulations of patients with obesity using their operational variables for (a) risk and (b) response. We will use this knowledge to stimulate a new narrative, understanding and vocabulary around obesity as a set of complex and chronic diseases.
Keywords:
Obesity, Diabetes, Treatment, Prediction, Biomarker

Involved staff

Managers

Department of Internal Medicine
Hospitals and clinical institutes, Faculty of Medicine

Contact persons

Faculty of Medicine
University of Tübingen
Faculty of Medicine
University of Tübingen

Local organizational units

Internal Medicine Department IV
Department of Internal Medicine
Hospitals and clinical institutes, Faculty of Medicine

Funders

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