Project STR/VA-CAL1 – VA-CAL Studie

Basic data

Acronym:
STR/VA-CAL1
Title:
VA-CAL Studie
Duration:
01/12/2020 to 31/12/2021
Abstract / short description:
The VA-CAL study aims to determine visual acuity as a function of different contrast and luminance conditions.
Currently, the clinical visual acuity test is only performed at a specific luminance (usually between 80-320 cd/m²) and with a maximum contrast of the optotype, which does not reflect the daily conditions. On cloudy days and even more on sunny days, the ambient luminance significantly exceeds the specified luminance for the visual acuity test. The clinically measured value therefore does not reflect the visual acuity during daily activities. Therefore, especially in glare-sensitive patients like completely color blind people, which have a rare hereditary visual disorder affecting the cone photoreceptors called achromatopsia, the visual acuity determined in these artificial conditions is often overestimated and higher than the patients feel in their daily lives.
The study thus aims to measure the visual acuity for different luminance and contrast conditions of everyday life to create a more reliable description of the visual performance and which might result in a clinical parameter valuable for clinical studies like the currently in Tuebingen conducted gene therapy for achromatopsia. Also, the benefit of edge filters, which filter out part of the short-wave light from the light spectrum, objectively examined for their advantages on visual acuity, especially for glare-sensitive patients.
Keywords:
Sehschärfe

Involved staff

Managers

Center for Ophthalmology
Hospitals and clinical institutes, Faculty of Medicine
Faculty of Medicine
University of Tübingen
Center for Ophthalmology
Hospitals and clinical institutes, Faculty of Medicine

Other staff

Department of Biology
Faculty of Science
Center for Ophthalmology
Hospitals and clinical institutes, Faculty of Medicine

Local organizational units

Research Center for Ophthalmology
Center for Ophthalmology
Hospitals and clinical institutes, Faculty of Medicine

Funders

Tübingen, Baden-Württemberg, Germany
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