Project TRR 240/1, A08 – Platelets

Basic data

Acronym:
TRR 240/1, A08
Title:
Platelets
Duration:
01/07/2018 to 30/06/2022
Abstract / short description:
This project will focus on regulation of the platelet lipidome. We will characterise the molecular mechanisms governing platelet lipid metabolism and its functional consequences on thrombo-inflammation, decipher the dynamic changes in the platelet lipidome under pathophysiological condi-tions, and its relevance for atheroprogression and organ ischaemia. We will combine transgenic hy-perlipidaemic mouse models, high-resolution platelet imaging, and lipidomics approaches to disclose the key players governing platelet lipid metabolism. Besides, novel therapeutic targets will be identified and validated in experimental studies.
Keywords:
Platelets
Lipidomics

Staff

Managers

Faculty of Science
University of Tübingen
Pharmaceutical Institute
Department of Pharmacy and Biochemistry, Faculty of Science

Contact persons

Faculty of Science
University of Tübingen
Institute of Applied Physics (IAP)
Department of Physics, Faculty of Science
Faculty of Medicine
University of Tübingen

Local organizational units

Pharmaceutical Institute
Department of Pharmacy and Biochemistry
Faculty of Science

Funders

Bonn, Nordrhein-Westfalen, Germany
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