Project Pathogen and host-derived lipid membranes governing Staphylococcus aureus-mediated skin inflammation

Basic data

Title:
Pathogen and host-derived lipid membranes governing Staphylococcus aureus-mediated skin inflammation
Duration:
01/08/2018 to 31/07/2021
Abstract / short description:
Human skin is colonized by a complex microbiome constantly releasing pro-inflammatory microbe-associated molecular pattern (MAMP) molecules. It has remained largely unclear how permanent skin inflammation is avoided while invading pathogens
still lead to rapid pro-inflammatory responses. Our project will help to elucidate key processes of bacterial MAMP releases and of skinbarrier function and it should inspire better clinical interventions against skin inflammation in AD patients and other chronic inflammatory skin diseases.
Keywords:
Skin infection
Staphylococcus aureus

Staff

Managers

Department of Dermatology
Hospitals and clinical institutes, Faculty of Medicine

Contact persons

Interfaculty Institute of Microbiology and Infection Medicine (IMIT)
Interfaculty Institutes

Local organizational units

Department of Dermatology
Hospitals and clinical institutes
Faculty of Medicine

Funders

Bonn, Nordrhein-Westfalen, Germany
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