Project MRI Biomarkers – Non-invasive renal volume and lipid quantification as biomarkers in patients with cardiovascular…

Basic data

Acronym:
MRI Biomarkers
Title:
Non-invasive renal volume and lipid quantification as biomarkers in patients with cardiovascular disease
Duration:
01/10/2015 to 31/05/2016
Abstract / short description:
Whole-body MRI offers comprehensive assessment and quantification of various body regions and disease
states and has been used in both clinical and scientific settings. The technology has also been
implemented in population-based studies to detect early disease stages and imaging biomarkers indicative
of increased risk of developing diseases in the future.
Parenchymal abnormalities of the kidneys are closely linked to the development and outcome of
cardiovascular disease (CVD). Renal sinus fat, as an example of ectopic perivascular fat depots, obstructs
the blood and lymph outflow of the kidney and is thus associated with both hypertension and chronic kidney
disease.
The purpose of this project is to develop independent kidney based morphometric and metabolic
biomarkers, which allow assessment of early renal abnormalities. Ultimately they may serve for individual
risk and outcome assessment in cardiovascular disease.
Keywords:
cardiovascular disease
Herzkreislauferkrankungen
Renal volume
lipid quantification
MRI

Involved staff

Managers

Faculty of Medicine
University of Tübingen

Contact persons

Faculty of Medicine
University of Tübingen

Local organizational units

Department of Diagnostic and Interventional Radiology
Department of Radiology
Hospitals and clinical institutes, Faculty of Medicine
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