Project Transcan 3 Verbund: HLA-Ligandomanalyse von ATRT-Tumorgewebeproben

Basic data

Title:
Transcan 3 Verbund: HLA-Ligandomanalyse von ATRT-Tumorgewebeproben
Duration:
01/04/2015 to 31/03/2018
Abstract / short description:
Atypical teratoid/rhabdoid tumors (ATRT) are rare but highly malignant neuroectodermal tumors. Here, we will analyze the ATRT peptidome by directly eluting peptides from tumor HLA molecules and sequence analysis via mass spectrometry. Subsequently, the most relevant peptides will be tested for immunogenicity in naïve CD8+ T cells from healthy donors and selected patients

Involved staff

Managers

Immunology
Interfaculty Institute for Cell Biology (IFIZ), Interfaculty Institutes

Local organizational units

Immunology
Interfaculty Institute for Cell Biology (IFIZ)
Interfaculty Institutes

Funders

Bonn, Nordrhein-Westfalen, Germany
Help

will be deleted permanently. This cannot be undone.